Аnaphylaxis – specific and nonspecific hypersensitivity

Specific and Nonspecific Outcomes

These interventions, practices, and disciplines are grouped together in this plan as mind and body* approaches because, from a research perspective, they all share a set of characteristics that create similar challenges in designing rigorous and definitive clinical investigations of their benefit and safety. For example, (1) it is generally difficult or impossible to mask practitioners and/or p...

A Study on Specific and Nonspecific Effects of Antisnake-Bite Serum

Sequence-specific inhibition of a nonspecific protease.

A nonspecific exopeptidase, aminopeptidase N (APN), is inhibited sequence-specifically by a synthetic host, cucurbit[7]uril (Q7), which binds with high affinity and specificity to N-terminal phenylalanine (Phe) and 4-(aminomethyl)phenylalanine (AMPhe) and prevents their removal from the peptide. Liquid chromatography experiments demonstrated that in the presence of excess Q7, APN quantitatively...

Quasi - Specific , or Nonspecific ? Specific , − Invertebrate Immune Systems

A specific mechanism of nonspecific inhibition.

Promiscuous small molecules plague screening libraries and hit lists. Previous work has found that several nonspecific compounds form submicrometer aggregates, and it has been suggested that this aggregate species is responsible for the inhibition of many different enzymes. It is not understood how aggregates inhibit their targets. To address this question, biophysical, kinetic, and microscopy ...